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Clenbuterol

Clenbuterol
Brand: So Pharma
Product Code: GSLDJN
Reward Points: 0
Availability: In Stock
Price: £13.00
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Manufacturer: So Pharma
Substance: Clenbuterol Hydrochloride
Packing: 50 tabs. (20 mcg/tab)

 

Clenbuterol (Clen) is a selective beta-2 agonist / antagonist and a bronchodilator. What this means is that it stimulates the beta-2 receptors. Of great importance is that Clenbuterol is a selective agonist beta-2 (because it works selectively on the beta-2-andrenergic-receptors), right? The thing is, Clenbuterol is selective ... like hitting a nail (the tactics to be your beta receptor-2) with a small hammer (the hammer is the Clen) ... therefore, leads to the beta-2 receptors selectively. Sorry if this seems repetitive, but it is very important to understand that before going ahead. Since Clenbuterol has little beta-1 stimulating ability, has the ability to reduce certain types of airway obstruction without much in the way of cardiovascular effect (more on that later), and so is used as a medicine for asthma.

What exactly dose a stimulant like Clenbuterol do when it stimulates the beta receptors? Well, serves to increase your body temperature a bit by increasing heat production in the mitochondria, increase basal metabolic rate, and decrease your appetite. This partly explains how Beta-2 agonists directly stimulate fat cells and increase lipolysis (fat loss). And also, because it is a beta-2 agent, Clenbuterol can decrease insulin sensitivity, unfortunately.

Clenbuterol is a very effective repartitioning agent, and this is what is most often used in athletic circles. It will increase your ratio of fat-free mass (FFM) to fat mass, decreasing fat and possibly increasing its mission.

Based on its rate of elimination from the body, and how much it takes to be effective for athletes, my recommendations are the same for men and women. You will have to take 20mcgs at sunrise, and then repeat the same dose later in the day, and then again on that day (if you find you can tolerate the effects). So start with 20mcgs, then repeat the dose two times the same day if you can tolerate (the effects secundariosdeterminará this hand shaking, sweating, etc. and classic stimulant sides). You can then start increasing the dose gradually. Personally, I would work my way up over 200mcg/day. 60-120mcg/day is an average dose. And keep your blood pressure at (or below) 140/90, while on Clenbuterol, just to be safe. If you go over that, lower the dose. Also want to know the temperature of your body, at sunrise, for the week before you start taking the Clenbuterol, and then monitor (again, as soon as you wake up) throughout your Clenbuterol regimen. When changing back to level before you start taking the Clenbuterol, you have to start taking your Benadryl or Ketotifen, as the decrease in body temperature back to original levels indicates the thermogenic effect is beginning to decline.

 

Clenbuterol can also cause a downregulation in testicular androgen receptors and pulmonary, cardiac and nerve receptors of the central beta-adrenergic agonists (6.) Possibly making steroids less effective (if there is decreased expression of the androgen receptor in elsewhere, then it is highly probable) while you are on Clenbuterol, but definitely Clenbuterol less effective over time and you take this medicine. To counter this, you can take some ketotifen every 3 weeks or 4 remaining in Clenbuterol. It is a prescription anti-histimines, so that will make you drowsy (take before bedtime). Basically, the way this works is the reduction of activity of beta-2 receptors, and restore receptor function.

 

Another option, if you are worried about receptor downgrade, is taking Benadryl, at around 50-100mgs/night before bed (every third week or so, for that week). Benadryl is sold as an antihistamine in the United States and / or a sleep aid elsewhere in the world. However, the beta receptors are embedded in the cell membrane phospholipids outside. The stability of the membrane has a lot to do with the proper functioning of the receptors. Methylation of the phospholipids is stimulated by the binding of beta agonists to their receptors. Methylated phospholipids are foreign to the body, and when the body recognizes as foreign, they broke with the phospholipase A2. This changes the structure of the outer membrane which results in desensitization of the beta receptors. Moreover, agents that inhibit phospholipase A2 slow desensitization.

Also, keep in mind that clenbuterol has some side effects. Not very good for your heart and can cause some issues there (enlargement of the ventricles, etc.) but most studies showing Clenbuterol to cause heart problems are with animals, and although the dose is almost similar to humans taken (in some studies is within the range of what would be twice the dose of human large ...) is important to remember that animals have more beta-2 receptors and cause certain strings if human beta-2 receptors may not. Clenbuterol causes cardiac hypertrophy and cardiac necrosis (cell death) to some extent, in some cases. Again though, many studies show the most significant, possibly irreversible, heart problems are with mg dosing. We humans take Clenbuterol in mcg doses.

 

if you want to duplicate the "theraputic" levels of Clenbuterol seen in more conservative studies, we would still be taking 1mcg/lb little more body weight twice a day. I suggest a little less than half that dose, however. Performance issues with Clenbuterol also vary. Some studies show reduced exercise (cardiovascular) performance with Clenbuterol, while others show that Clenbuterol can alleviate exercise induced asthma! It is clear that this compound will have different effects on different people, and I suspect many of them specific sports. Many bodybuilders claim that Clenbuterol makes it difficult for them to do cardio, yet I can play a full game of rugby on it. You need to find out how you react and adapt personal dose.

Finally, this brings the issue of cramps while on Clenbuterol. Most of us are athletes who use Clenbuterol during the season and the offseason, and one of my friends even said that gives him more "wind" (cardiovascular endurance). Drink plenty of water every day and you should be fine. If you are really interested, you can take some extra minerals and taurine, since Clenbuterol depletes taurine that most if not all beta agonists. It is not renagado of nothing but my usual vitamins and minerals.

 

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